If you're constantly tired no matter how much you sleep, struggling with brain fog, or just don't feel like yourself anymore, an underlying hormonal imbalance may be part of the picture. As estrogen, progesterone, and testosterone levels shift with age, stress, or menopause and andropause, fatigue is often one of the first and most disruptive symptoms.
At Dermatology Associates, PC, Dr. Sonya F. Campbell Johnson offers physician-led Hormone Replacement Therapy (HRT) as part of a comprehensive approach to whole-body wellness — evaluating your hormone levels, symptoms, and health history to build a treatment plan aimed at restoring your energy, mental clarity, and quality of life.

Fatigue has many possible causes, and it's important to understand which kind you're experiencing before starting treatment.
Hormone-driven fatigue typically develops gradually, alongside other signs of hormonal decline — sleep disruption, mood changes, low libido, weight changes, or skin and hair changes. It often responds well to hormone optimization once levels are properly evaluated.
Chronic Fatigue Syndrome (ME/CFS) is a distinct, diagnosed medical condition involving persistent, unexplained exhaustion not resolved by rest, often with additional symptoms like post-exertional malaise or cognitive difficulty. It requires its own diagnostic workup, and hormone therapy alone isn't a treatment for ME/CFS.
During your consultation, Dr. Campbell Johnson will review your symptoms and lab work to determine whether hormonal imbalance is a contributing factor to your fatigue — and refer you appropriately if further evaluation is needed.

Custom-tailored Hormone Therapy Designer for Lasting Comfort and Health
Pellet Hormone Therapy: Small implants placed beneath the skin, delivering a steady hormone release for 3-6 months. Best for patients who want consistent, steady energy without remembering a daily dose — ideal if you've felt your energy "crash" between doses on other methods.
Injectable Hormone Therapy
Hormones administered via injections every 1-4 weeks, offering precise level control. A good fit for patients who want more direct control over dosing and are comfortable with a clinic visit every 1–4 weeks — often preferred by those who want to fine-tune levels quickly if fatigue symptoms aren't improving.
Oral Hormone Therapy: Easy-to-use pills, taken daily, for those preferring a simple daily routine. Best for patients who prefer a simple, familiar daily-pill routine and want to start with a lower-commitment option before considering pellets or injections.
Topical/Cream Hormone Therapy: Applied directly to the skin for localized absorption with adjustable dosage control. A good fit for patients who want adjustable, localized dosing and prefer to avoid needles or implants — easy to titrate up or down as energy and symptoms change.
Ready to Feel Like Yourself Again?
If fatigue, brain fog, or low energy have become your new normal, a simple hormone evaluation can tell you what's really going on. Dr. Campbell Johnson will review your symptoms and lab work to build a treatment plan tailored to you — not a one-size-fits-all protocol.
Bioidentical hormones are chemically identical to the ones our bodies produce, supporting natural body functions with minimal side effects.
For many patients, yes — when fatigue is linked to declining hormone levels, restoring balance through HRT can significantly improve energy, mental clarity, and overall well-being. A proper evaluation is the first step to confirm hormones are a contributing factor.
Yes. Hormone-related fatigue is tied to measurable hormonal decline and often improves with treatment. Chronic Fatigue Syndrome (ME/CFS) is a separate, complex condition that requires its own diagnostic process. Dr. Campbell Johnson will help determine which applies to you.
As with any medical treatment, HRT carries risks that vary by individual, including a potential increase in risk of blood clots, stroke, or certain cancers — particularly for those starting treatment later in life. Your provider will review your personal risk factors before recommending treatment.
Declining estrogen levels contribute to skin thinning, dryness, and reduced collagen production. HRT can restore skin hydration, elasticity, and thickness.
Men and women experiencing symptoms like fatigue, mood changes, sleep issues, low libido, and more can benefit from HRT.
Bioidentical hormones replicate your body’s natural hormones, enhancing safety and effectiveness compared to synthetic options.
Most patients notice improvement within days to weeks, experiencing increased energy, better mood, and enhanced overall health.
If you choose to discontinue, symptoms may return over time as hormone levels revert.
Dermatology Associates, PC operates three convenient locations across Indiana — our flagship office in Indianapolis (Marion County), our Batesville office serving Ripley County and southeastern Indiana, and our Tipton office serving Tipton County and surrounding communities including Kempton, Sharpsville, and Atlanta, IN.
Can't make it in person? Call (317) 257-1484 to discuss your options with our team.